STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KAE1-2tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (377 aa)    
Predicted Functional Partners:
AMAG_00605
Uncharacterized protein.
   
 0.997
AMAG_11956
Uncharacterized protein; Belongs to the CGI121/TPRKB family.
    
 0.996
AMAG_03111
BUD32 protein kinase.
  
 0.991
AMAG_10382
BUD32 protein kinase.
  
 0.991
AMAG_09089
Uncharacterized protein; Belongs to the CGI121/TPRKB family.
    
 0.990
AMAG_12574
Sua5/YciO/YrdC/YwlC family protein.
  
 
 0.857
AMAG_14531
Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
  
 
 0.857
AMAG_05187
Dephospho-CoA kinase.
    
 0.713
AMAG_16080
Dephospho-CoA kinase.
    
 0.713
AMAG_07584
LMWPc domain-containing protein.
    
  0.703
Your Current Organism:
Allomyces macrogynus
NCBI taxonomy Id: 578462
Other names: A. macrogynus ATCC 38327, Allomyces macrogynus ATCC 38327
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.