AMAG_09721 protein (Allomyces macrogynus) - STRING interaction network

Nodes:

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second shell of interactors

Node Content

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proteins of unknown 3D structure

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Edges:

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

AMAG_09721

KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (415 aa)

Predicted Functional Partners:

AMAG_13362

0.999

AMAG_13615

0.999

AMAG_01691

0.998

AMAG_04183

0.998

AMAG_11302

0.998

AMAG_19806

0.998

AMAG_15149

0.998

AMAG_17183

0.998

AMAG_00054

0.997

AMAG_01490

0.997

Your Current Organism:

Allomyces macrogynus

NCBI taxonomy Id: 578462
Other names: A. macrogynus ATCC 38327, Allomyces macrogynus ATCC 38327

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMAG_00054	AMAG_01490	A0A0L0RVF6	A0A0L0RZV8	Uncharacterized protein.	Uncharacterized protein.	0.603
AMAG_00054	AMAG_01691	A0A0L0RVF6	A0A0L0RZQ9	Uncharacterized protein.	Sas10 domain-containing protein.	0.990
AMAG_00054	AMAG_04183	A0A0L0RVF6	A0A0L0S887	Uncharacterized protein.	Sas10 domain-containing protein.	0.990
AMAG_00054	AMAG_09721	A0A0L0RVF6	A0A0L0ST57	Uncharacterized protein.	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.	0.997
AMAG_00054	AMAG_11302	A0A0L0RVF6	A0A0L0SWP2	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.995
AMAG_00054	AMAG_13362	A0A0L0RVF6	A0A0L0T1U0	Uncharacterized protein.	Uncharacterized protein.	0.993
AMAG_00054	AMAG_13615	A0A0L0RVF6	A0A0L0T3D1	Uncharacterized protein.	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	0.993
AMAG_00054	AMAG_15149	A0A0L0RVF6	A0A0L0T5V8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.995
AMAG_00054	AMAG_17183	A0A0L0RVF6	A0A0L0TEH6	Uncharacterized protein.	Uncharacterized protein.	0.981
AMAG_00054	AMAG_19806	A0A0L0RVF6	A0A0L0T106	Uncharacterized protein.	Uncharacterized protein.	0.981
AMAG_01490	AMAG_00054	A0A0L0RZV8	A0A0L0RVF6	Uncharacterized protein.	Uncharacterized protein.	0.603
AMAG_01490	AMAG_01691	A0A0L0RZV8	A0A0L0RZQ9	Uncharacterized protein.	Sas10 domain-containing protein.	0.903
AMAG_01490	AMAG_04183	A0A0L0RZV8	A0A0L0S887	Uncharacterized protein.	Sas10 domain-containing protein.	0.903
AMAG_01490	AMAG_09721	A0A0L0RZV8	A0A0L0ST57	Uncharacterized protein.	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.	0.997
AMAG_01490	AMAG_11302	A0A0L0RZV8	A0A0L0SWP2	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.869
AMAG_01490	AMAG_13362	A0A0L0RZV8	A0A0L0T1U0	Uncharacterized protein.	Uncharacterized protein.	0.947
AMAG_01490	AMAG_13615	A0A0L0RZV8	A0A0L0T3D1	Uncharacterized protein.	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	0.947
AMAG_01490	AMAG_15149	A0A0L0RZV8	A0A0L0T5V8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.869
AMAG_01490	AMAG_17183	A0A0L0RZV8	A0A0L0TEH6	Uncharacterized protein.	Uncharacterized protein.	0.881
AMAG_01490	AMAG_19806	A0A0L0RZV8	A0A0L0T106	Uncharacterized protein.	Uncharacterized protein.	0.881

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Network Stats

number of nodes:

11

number of edges:

10

average node degree:

1.82

avg. local clustering coefficient:

0.909

expected number of edges:

10

PPI enrichment p-value:

0.6

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006783

Heme biosynthetic process

7 of 28

2.09

4.42

9.99e-11

GO:0006782

Protoporphyrinogen IX biosynthetic process

5 of 21

2.07

3.26

1.08e-07

GO:0019438

Aromatic compound biosynthetic process

8 of 319

1.1

1.26

2.55e-06

GO:0018130

Heterocycle biosynthetic process

8 of 362

1.04

1.14

6.20e-06

GO:1901362

Organic cyclic compound biosynthetic process

8 of 369

1.03

1.12

6.64e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004655

Porphobilinogen synthase activity

2 of 2

2.7

0.98

0.0165

GO:0016836

Hydro-lyase activity

3 of 49

1.48

0.65

0.0475

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

6 of 374

0.9

0.66

0.0049

GO:0005737

Cytoplasm

9 of 1536

0.46

0.32

0.0228

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6283

Porphyrin biosynthesis, and Cytochrome C assembly protein

6 of 10

2.47

5.01

1.08e-10

CL:6285

Siroheme metabolic process, and Cytochrome C assembly protein

3 of 5

2.47

2.28

5.30e-05

CL:1639

Fatty acid biosynthesis, and Acyl transferase

2 of 6

2.22

1.02

0.0125

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

dti00860

Porphyrin and chlorophyll metabolism

6 of 48

1.79

2.99

3.37e-08

dti01110

Biosynthesis of secondary metabolites

7 of 347

1.0

0.99

6.41e-05

dti01120

Microbial metabolism in diverse environments

6 of 317

0.97

0.85

0.00053

dti01100

Metabolic pathways

7 of 844

0.62

0.43

0.0109

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-168249

Innate Immune System

2 of 9

2.04

1.31

0.0030

MAP-168256

Immune System

2 of 20

1.7

1.08

0.0062

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0627

Porphyrin biosynthesis

6 of 12

2.4

5.06

5.03e-11

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR030656

Delta-aminolevulinic acid dehydratase, active site

2 of 2

2.7

0.79

0.0372

IPR016036

Malonyl-CoA ACP transacylase, ACP-binding

2 of 3

2.52

0.79

0.0372

IPR014043

Acyl transferase

2 of 3

2.52

0.79

0.0372

IPR001731

Delta-aminolevulinic acid dehydratase

2 of 2

2.7

0.79

0.0372

IPR001227

Acyl transferase domain superfamily

2 of 3

2.52

0.79

0.0372

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01004

Delta-aminolevulinic acid dehydratase

2 of 2

2.7

1.39

0.0030

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