AMAG_13728 protein (Allomyces macrogynus) - STRING interaction network

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second shell of interactors

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Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

AMAG_13728

Hexosyltransferase. (492 aa)

Predicted Functional Partners:

AMAG_08747

0.765

AMAG_10170

0.765

AMAG_11038

0.730

AMAG_11651

0.730

AMAG_10781

0.487

Your Current Organism:

Allomyces macrogynus

NCBI taxonomy Id: 578462
Other names: A. macrogynus ATCC 38327, Allomyces macrogynus ATCC 38327

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMAG_08747	AMAG_11038	A0A0L0SMP2	A0A0L0SSC3	Uncharacterized protein.	Uncharacterized protein.	0.766
AMAG_08747	AMAG_11651	A0A0L0SMP2	A0A0L0SVC4	Uncharacterized protein.	Beta-hexosaminidase.	0.766
AMAG_08747	AMAG_13728	A0A0L0SMP2	A0A0L0T3R8	Uncharacterized protein.	Hexosyltransferase.	0.765
AMAG_10170	AMAG_11038	A0A0L0SR31	A0A0L0SSC3	Uncharacterized protein.	Uncharacterized protein.	0.766
AMAG_10170	AMAG_11651	A0A0L0SR31	A0A0L0SVC4	Uncharacterized protein.	Beta-hexosaminidase.	0.766
AMAG_10170	AMAG_13728	A0A0L0SR31	A0A0L0T3R8	Uncharacterized protein.	Hexosyltransferase.	0.765
AMAG_10781	AMAG_13728	A0A0L0SRL7	A0A0L0T3R8	Uncharacterized protein.	Hexosyltransferase.	0.487
AMAG_11038	AMAG_08747	A0A0L0SSC3	A0A0L0SMP2	Uncharacterized protein.	Uncharacterized protein.	0.766
AMAG_11038	AMAG_10170	A0A0L0SSC3	A0A0L0SR31	Uncharacterized protein.	Uncharacterized protein.	0.766
AMAG_11038	AMAG_13728	A0A0L0SSC3	A0A0L0T3R8	Uncharacterized protein.	Hexosyltransferase.	0.730
AMAG_11651	AMAG_08747	A0A0L0SVC4	A0A0L0SMP2	Beta-hexosaminidase.	Uncharacterized protein.	0.766
AMAG_11651	AMAG_10170	A0A0L0SVC4	A0A0L0SR31	Beta-hexosaminidase.	Uncharacterized protein.	0.766
AMAG_11651	AMAG_13728	A0A0L0SVC4	A0A0L0T3R8	Beta-hexosaminidase.	Hexosyltransferase.	0.730
AMAG_13728	AMAG_08747	A0A0L0T3R8	A0A0L0SMP2	Hexosyltransferase.	Uncharacterized protein.	0.765
AMAG_13728	AMAG_10170	A0A0L0T3R8	A0A0L0SR31	Hexosyltransferase.	Uncharacterized protein.	0.765
AMAG_13728	AMAG_10781	A0A0L0T3R8	A0A0L0SRL7	Hexosyltransferase.	Uncharacterized protein.	0.487
AMAG_13728	AMAG_11038	A0A0L0T3R8	A0A0L0SSC3	Hexosyltransferase.	Uncharacterized protein.	0.730
AMAG_13728	AMAG_11651	A0A0L0T3R8	A0A0L0SVC4	Hexosyltransferase.	Beta-hexosaminidase.	0.730

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.889

expected number of edges:

19

PPI enrichment p-value:

0.0903

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046710

GDP metabolic process

3 of 7

2.86

2.26

7.37e-05

GO:0046037

GMP metabolic process

3 of 13

2.59

2.04

0.00017

GO:0046940

Nucleoside monophosphate phosphorylation

3 of 29

2.24

1.59

0.0010

GO:0010737

Protein kinase A signaling

2 of 9

2.58

1.31

0.0041

GO:0009150

Purine ribonucleotide metabolic process

4 of 242

1.45

1.07

0.0033

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004679

AMP-activated protein kinase activity

2 of 7

2.68

0.96

0.0185

GO:0004385

Guanylate kinase activity

2 of 6

2.75

0.96

0.0185

GO:0004691

cAMP-dependent protein kinase activity

2 of 8

2.63

0.95

0.0185

GO:0004115

3,5-cyclic-AMP phosphodiesterase activity

2 of 21

2.21

0.88

0.0238

GO:0016301

Kinase activity

5 of 625

1.13

0.68

0.0185

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005952

cAMP-dependent protein kinase complex

2 of 12

2.45

0.88

0.0253

GO:0030141

Secretory granule

2 of 15

2.35

0.87

0.0253

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15653

GDP metabolic process, and Dpy-30 motif

4 of 5

3.13

4.21

2.11e-08

CL:444

Mixed, incl. Atos-like, conserved domain, and Response to mechanical stimulus

2 of 6

2.75

1.48

0.0020

CL:3205

cAMP-dependent protein kinase complex, and Protein kinase, C-terminal

2 of 24

2.15

0.91

0.0200

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

6 of 223

1.66

2.52

2.06e-07

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-418555

G alpha (s) signalling events

4 of 31

2.34

2.82

3.40e-06

MAP-111885

Opioid Signalling

4 of 49

2.14

2.51

9.45e-06

MAP-438064

Post NMDA receptor activation events

3 of 24

2.33

2.11

9.47e-05

MAP-111997

CaM pathway

3 of 25

2.31

2.11

9.47e-05

MAP-111933

Calmodulin induced events

3 of 25

2.31

2.11

9.47e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0002177

Manchette

2 of 4

2.93

1.24

0.0057

GOCC:0001669

Acrosomal vesicle

2 of 4

2.93

1.24

0.0057

GOCC:0005952

cAMP-dependent protein kinase complex

2 of 12

2.45

1.09

0.0099

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00471

Metal dependent phosphohydrolases with conserved HD motif.

2 of 26

2.11

0.78

0.0360

SM00015

Short calmodulin-binding motif containing conserved Ile and Gln residues.

2 of 20

2.23

0.78

0.0360

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