STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ArsBUncharacterized protein ArsB. (552 aa)    
Predicted Functional Partners:
F0Z7S7_DICPU
LMWPc domain-containing protein.
  
 
 0.927
ArsA
ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]
    
 0.904
F1A2E2_DICPU
FMN_red domain-containing protein.
  
  
 0.784
F1A4B3_DICPU
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
      
 0.591
F0ZNV1_DICPU
Sod_Cu domain-containing protein.
     
 0.555
F0ZJ64_DICPU
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
     
 0.549
F0ZME6_DICPU
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
     
 0.406
Your Current Organism:
Dictyostelium purpureum
NCBI taxonomy Id: 5786
Other names: D. purpureum
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