STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F0ZA15_DICPUUncharacterized protein. (151 aa)    
Predicted Functional Partners:
F0Z9W1_DICPU
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.950
F0ZT58_DICPU
RNA polymerase II core subunit.
   
 0.911
F0ZFN5_DICPU
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.880
F0ZA16_DICPU
Histone H3.
 
 
 0.869
F1A4E1_DICPU
Histone H3.
 
 
 0.868
F1A4S1_DICPU
Histone H2A; Belongs to the histone H2A family.
    
 0.867
F0ZQB3_DICPU
Histone domain-containing protein.
 
 
 0.866
F0ZUT7_DICPU
Histone domain-containing protein.
   
 0.862
F0ZGZ5_DICPU
Uncharacterized protein.
   
 
0.801
F1A117_DICPU
Uncharacterized protein.
  
 
 0.791
Your Current Organism:
Dictyostelium purpureum
NCBI taxonomy Id: 5786
Other names: D. purpureum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.