STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (362 aa)    
Predicted Functional Partners:
SFN09342.1
Pyruvate dehydrogenase E1 component beta subunit.
 0.999
SFN33951.1
Dihydrolipoamide dehydrogenase.
 
 0.999
SFN30670.1
2-oxoisovalerate dehydrogenase E1 component.
 
0.988
SFN09358.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.986
SFN33979.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.977
SFN14575.1
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.962
SFN14564.1
Dihydrolipoamide dehydrogenase.
 
 
 0.928
SFN09714.1
Dihydrolipoamide dehydrogenase.
 
 
 0.902
SFN01090.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.825
SFM96757.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.811
Your Current Organism:
Dokdonella immobilis
NCBI taxonomy Id: 578942
Other names: CGMCC 1.7659, D. immobilis, Dokdonella immobilis Liu et al. 2013, Dokdonella sp. LM2-5, JCM 15763, strain LM2-5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.