STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX71891.1PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat protein; KEGG: mba:Mbar_A3390 hypothetical protein. (409 aa)    
Predicted Functional Partners:
ACX72861.1
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; Tetratricopeptide repeat; KEGG: tga:TGAM_0974 serine/threonine protein kinase.
  
 0.988
tbp
TATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
 0.963
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 0.944
ACX73242.1
PFAM: GTP-binding protein HSR1-related; KEGG: mja:MJ1464 GTP-binding protein.
  
 0.940
ACX72992.1
PFAM: glucose-methanol-choline oxidoreductase; KEGG: mja:MJ1450 hypothetical protein.
   
 0.926
ACX72101.1
PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: mja:MJ0047 putative mRNA 3'-end processing factor 1.
    
 0.906
ACX73507.1
PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: mja:MJ0162 putative mRNA 3'-end processing factor 3.
    
 0.906
ACX71980.1
PFAM: metallophosphoesterase; KEGG: mja:MJ0912 hypothetical protein.
  
 0.895
ACX72205.1
TIGRFAM: DNA helicase; SMART: DEAD-like helicase; KEGG: mja:MJ0104 DNA-binding protein.
  
 0.895
tfe
Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...]
    
 0.887
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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