node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACX71885.1 | ACX71898.1 | Metvu_0012 | Metvu_0026 | biotin/acetyl-CoA-carboxylase ligase; KEGG: mja:MJ1619 biotin operon repressor/biotin--[acetyl-CoA-carboxylase] ligase (BirA); TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein. | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | 0.940 |
ACX71885.1 | ACX72132.1 | Metvu_0012 | Metvu_0265 | biotin/acetyl-CoA-carboxylase ligase; KEGG: mja:MJ1619 biotin operon repressor/biotin--[acetyl-CoA-carboxylase] ligase (BirA); TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.520 |
ACX71885.1 | bioA | Metvu_0012 | Metvu_0858 | biotin/acetyl-CoA-carboxylase ligase; KEGG: mja:MJ1619 biotin operon repressor/biotin--[acetyl-CoA-carboxylase] ligase (BirA); TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.504 |
ACX71885.1 | bioB | Metvu_0012 | Metvu_0267 | biotin/acetyl-CoA-carboxylase ligase; KEGG: mja:MJ1619 biotin operon repressor/biotin--[acetyl-CoA-carboxylase] ligase (BirA); TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.938 |
ACX71885.1 | bioD | Metvu_0012 | Metvu_1325 | biotin/acetyl-CoA-carboxylase ligase; KEGG: mja:MJ1619 biotin operon repressor/biotin--[acetyl-CoA-carboxylase] ligase (BirA); TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.561 |
ACX71894.1 | ACX71896.1 | Metvu_0021 | Metvu_0023 | PFAM: Uncharacterised conserved protein UCP019375; KEGG: mja:MJ0787 hypothetical protein. | KEGG: mja:MJ0786 hypothetical protein. | 0.814 |
ACX71894.1 | ACX71898.1 | Metvu_0021 | Metvu_0026 | PFAM: Uncharacterised conserved protein UCP019375; KEGG: mja:MJ0787 hypothetical protein. | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | 0.986 |
ACX71894.1 | bioB | Metvu_0021 | Metvu_0267 | PFAM: Uncharacterised conserved protein UCP019375; KEGG: mja:MJ0787 hypothetical protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.528 |
ACX71894.1 | hmd | Metvu_0021 | Metvu_0027 | PFAM: Uncharacterised conserved protein UCP019375; KEGG: mja:MJ0787 hypothetical protein. | Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. | 0.729 |
ACX71896.1 | ACX71894.1 | Metvu_0023 | Metvu_0021 | KEGG: mja:MJ0786 hypothetical protein. | PFAM: Uncharacterised conserved protein UCP019375; KEGG: mja:MJ0787 hypothetical protein. | 0.814 |
ACX71896.1 | ACX71898.1 | Metvu_0023 | Metvu_0026 | KEGG: mja:MJ0786 hypothetical protein. | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | 0.871 |
ACX71896.1 | hmd | Metvu_0023 | Metvu_0027 | KEGG: mja:MJ0786 hypothetical protein. | Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. | 0.451 |
ACX71898.1 | ACX71885.1 | Metvu_0026 | Metvu_0012 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | biotin/acetyl-CoA-carboxylase ligase; KEGG: mja:MJ1619 biotin operon repressor/biotin--[acetyl-CoA-carboxylase] ligase (BirA); TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein. | 0.940 |
ACX71898.1 | ACX71894.1 | Metvu_0026 | Metvu_0021 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | PFAM: Uncharacterised conserved protein UCP019375; KEGG: mja:MJ0787 hypothetical protein. | 0.986 |
ACX71898.1 | ACX71896.1 | Metvu_0026 | Metvu_0023 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | KEGG: mja:MJ0786 hypothetical protein. | 0.871 |
ACX71898.1 | ACX72132.1 | Metvu_0026 | Metvu_0265 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.751 |
ACX71898.1 | ACX73273.1 | Metvu_0026 | Metvu_1420 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | TIGRFAM: coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein; PFAM: H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase; KEGG: mja:MJ0715 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein. | 0.740 |
ACX71898.1 | bioA | Metvu_0026 | Metvu_0858 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.834 |
ACX71898.1 | bioB | Metvu_0026 | Metvu_0267 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.926 |
ACX71898.1 | bioD | Metvu_0026 | Metvu_1325 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.991 |