Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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tfeTranscription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...] (184 aa)    
Predicted Functional Partners:
tbp
TATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
  
 0.989
tfb
Transcription factor TFIIB cyclin-releated protein; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
  
 
 0.987
ACX72249.1
Transcription termination factor Tfs; KEGG: mja:MJ1148 transcription-associated protein ('TFIIS'); TIGRFAM: transcription factor S; PFAM: DNA-directed RNA polymerase, M/15 kDa subunit; Transcription factor TFIIS; SMART: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
  
 
 0.980
ACX71908.1
PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: mfe:Mefer_1029 protein of unknown function DUF201.
 
     0.969
rpoN
RNA polymerase, N/8 Kd subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
  
 
 0.968
ACX73487.1
PFAM: RNA polymerase insert; RNA polymerase dimerisation; SMART: RNA polymerase RpoA/D/Rpb3-type; KEGG: mja:MJ0192 DNA-directed RNA polymerase, subunit D (RpoD).
  
 
 0.966
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
  
 
 0.963
rpoP
RNA polymerase Rbp10; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
    
 0.959
ACX73587.1
SMART: helicase c2; DEAD-like helicase; KEGG: mja:MJ0942 ATP-dependent DNA helicase DinG, putative (DinG).
   
 0.956
ACX73482.1
PFAM: RNA polymerase Rpb6; KEGG: mja:MJ0197 DNA-directed RNA polymerase, subunit K (RpoK).
    
 0.953
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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