STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX71914.1PFAM: peptidase M48 Ste24p; KEGG: csc:Csac_0642 peptidase M48, Ste24p. (536 aa)    
Predicted Functional Partners:
ACX73393.1
PFAM: phosphoesterase RecJ domain protein; RNA binding S1 domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mja:MJ1198 hypothetical protein.
  
 
 0.829
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
   
 
 0.670
nth
DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
     
 0.617
ACX71912.1
KEGG: mja:MJ0772 hypothetical protein.
       0.614
ACX71913.1
TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mfe:Mefer_1034 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
       0.614
ACX73152.1
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: mja:MJ0999 thermosome (ths).
  
  
 0.608
ACX71980.1
PFAM: metallophosphoesterase; KEGG: mja:MJ0912 hypothetical protein.
  
 
 
 0.521
ACX73321.1
TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase; PFAM: hydroxymethylglutaryl-coenzyme A reductase; KEGG: mja:MJ0705 3-hydroxy-3-methylglutaryl coenzyme A reductase; Belongs to the HMG-CoA reductase family.
  
 
 0.492
ACX73068.1
KEGG: mfe:Mefer_0117 peptidase S16, Lon-like protease; TIGRFAM: peptidase S16, Lon-like protease; PFAM: peptidase S16 lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family.
  
 
 0.463
ACX72205.1
TIGRFAM: DNA helicase; SMART: DEAD-like helicase; KEGG: mja:MJ0104 DNA-binding protein.
    
 
 0.458
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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