Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX71915.1PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ1620 hypothetical protein. (498 aa)    
Predicted Functional Partners:
ACX72351.1
TIGRFAM: siroheme synthase; KEGG: mja:MJ0140 hypothetical protein.
     
 0.748
ACX72303.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ0745 hypothetical protein.
 
  
 0.709
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.697
ACX72298.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ0739 hypothetical protein.
 
  
 0.688
ACX72827.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ0150 hypothetical protein.
 
  
 0.652
ACX72984.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ0716m hypothetical protein.
 
  
 0.632
ACX72140.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ0855 hypothetical protein.
  
  
 0.529
ACX73246.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ1460 hypothetical protein.
  
  
 0.529
ACX73265.1
PFAM: 4-vinyl reductase 4VR; KEGG: mja:MJ1460 hypothetical protein.
  
  
 0.529
ACX73500.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mfe:Mefer_1356 radical SAM domain protein.
 
  
 0.478
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (26%) [HD]