STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACX71925.1TIGRFAM: rfaE bifunctional protein; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: mfe:Mefer_0532 RfaE bifunctional protein. (157 aa)    
Predicted Functional Partners:
ACX71926.1
PFAM: PfkB domain protein; Phosphomethylpyrimidine kinase type-1; KEGG: mfe:Mefer_0531 PfkB domain protein.
   
 0.997
ACX71928.1
TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: mfe:Mefer_0530 histidinol-phosphate phosphatase family protein.
 
 
  0.995
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
      0.984
ACX71941.1
TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; dTDP-4-dehydrorhamnose reductase; KEGG: mfe:Mefer_0514 ADP-L-glycero-D-manno-heptose-6-epimerase.
  
 
 0.918
ACX71927.1
KEGG: mja:MJ0023 hypothetical protein.
       0.670
ACX71943.1
PFAM: glycosyl transferase family 9; KEGG: mfe:Mefer_0512 glycosyl transferase family 9.
  
     0.617
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
     
 0.596
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
     
 0.498
ACX73305.1
PFAM: aminotransferase class V; KEGG: mja:MJ0959 aspartate aminotransferase (AspC).
  
  
 0.453
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
      
 0.445
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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