STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX71942.1PFAM: glycosyl transferase group 1; KEGG: mth:MTH173 LPS biosynthesis RfbU related protein. (379 aa)    
Predicted Functional Partners:
ACX73266.1
TIGRFAM: alpha-glucan phosphorylase; KEGG: mfe:Mefer_1323 alpha-glucan phosphorylase.
  
 
 0.789
ACX71943.1
PFAM: glycosyl transferase family 9; KEGG: mfe:Mefer_0512 glycosyl transferase family 9.
       0.773
ACX71941.1
TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; dTDP-4-dehydrorhamnose reductase; KEGG: mfe:Mefer_0514 ADP-L-glycero-D-manno-heptose-6-epimerase.
 
  
 0.741
ACX72861.1
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; Tetratricopeptide repeat; KEGG: tga:TGAM_0974 serine/threonine protein kinase.
  
 
 0.739
ACX72031.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: mja:MJ1116 asparagine synthetase (AsnB).
 
  
 0.709
ACX72264.1
PFAM: polysaccharide biosynthesis protein; KEGG: tko:TK1719 capsular polysaccharide biosynthesis protein.
 
  
 0.683
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 
 
 0.669
ACX71945.1
KEGG: mja:MJ1071 hypothetical protein.
     
 0.658
ACX72865.1
PFAM: DEAD/DEAH box helicase domain protein; ERCC4 domain protein; helix-hairpin-helix motif; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; Helix-hairpin-helix DNA-binding class 1; KEGG: mja:MJ1505 Hef nuclease.
  
 
 
 0.649
ACX71930.1
Nucleotide sugar dehydrogenase; KEGG: mja:MJ1054 UDP-glucose dehydrogenase, putative; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SMART: Hedgehog/intein hint domain protein.
 
  
 0.639
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.