STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX71977.1PFAM: CobN/magnesium chelatase; KEGG: mja:MJ0908 cobalamin biosynthesis protein (CobN). (1230 aa)    
Predicted Functional Partners:
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
 
 0.955
ACX73119.1
PFAM: CobN/magnesium chelatase; KEGG: mfe:Mefer_0187 magnesium chelatase.
  
  
 
0.909
ACX71979.1
KEGG: mja:MJ0911 magnesium-chelatase subunit (ChlI); PFAM: ATPase associated with various cellular activities AAA_5; magnesium chelatase ChlI subunit; SMART: AAA ATPase.
 
  
 0.881
ACX72113.1
TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mfe:Mefer_0587 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit.
  
  
 0.675
ACX71978.1
PFAM: Protein of unknown function DUF104; KEGG: mja:MJECL31 hypothetical protein.
       0.601
ACX73599.1
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: mja:MJ0930 precorrin-8X methylmutase.
 
  
 0.558
ACX72620.1
KEGG: mja:MJ1488 hypothetical protein.
  
  
 0.531
ACX72115.1
TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; KEGG: mja:MJ1520 bacteriochlorophyll synthase 43 kDa subunit (ChlP).
  
  
 0.520
ACX72329.1
Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
  
  
 0.520
ACX73367.1
KEGG: mja:MJ1182 hypothetical protein.
  
  
 0.520
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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