STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX71996.1PFAM: PP-loop domain protein; KEGG: mja:MJ0830 hypothetical protein. (250 aa)    
Predicted Functional Partners:
ACX73510.1
PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: mja:MJ0165 hypothetical protein.
 
  
 0.977
ACX72602.1
PFAM: protein of unknown function DUF111; KEGG: mja:MJ1387 hypothetical protein; Belongs to the LarC family.
  
 0.950
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
    0.941
nth
DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
    0.718
ACX73468.1
PFAM: Protein of unknown function DUF531; KEGG: mfe:Mefer_0457 protein of unknown function DUF531.
       0.589
ACX71998.1
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mja:MJ0831 hypothetical protein.
  
    0.572
ACX71997.1
Hypothetical protein.
       0.570
ACX73174.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: mja:MJ1569 cobalt transport protein CbiM.
  
    0.559
ACX73175.1
KEGG: mja:MJ1570 hypothetical protein.
  
    0.559
ACX71898.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0785 biotin synthase.
  
    0.469
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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