STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72028.1KEGG: mfe:Mefer_0274 tyrosine protein kinase. (219 aa)    
Predicted Functional Partners:
ACX72029.1
PFAM: protein of unknown function DUF75; KEGG: mja:MJ1210 hypothetical protein.
       0.697
ACX73225.1
KEGG: mja:MJ1212 CDP-diacylglycerol--serine O-phosphatidyltransferase (PssA); TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.648
ACX72280.1
KEGG: mja:MJ1399 hypothetical protein; Belongs to the UPF0200 family.
 
     0.581
ACX72748.1
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
     0.554
ACX73134.1
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
     
 0.547
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
     
 0.537
ACX72160.1
PFAM: protein of unknown function DUF354; KEGG: mfe:Mefer_1405 protein of unknown function DUF354.
  
     0.491
ACX72744.1
PFAM: Protein of unknown function DUF54; KEGG: mfe:Mefer_0550 protein of unknown function DUF54; Belongs to the UPF0201 family.
       0.481
ACX72927.1
PFAM: peptidase M50; KEGG: mja:MJ0971 hypothetical protein.
  
     0.472
mer
5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
       0.444
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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