node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACX72104.1 | prs | Metvu_0237 | Metvu_1388 | PFAM: phosphoribosyltransferase; KEGG: mja:MJ1646 orotate phosphoribosyltransferase-like protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.825 |
ACX72104.1 | pyrD | Metvu_0237 | Metvu_1011 | PFAM: phosphoribosyltransferase; KEGG: mja:MJ1646 orotate phosphoribosyltransferase-like protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.914 |
ACX72104.1 | pyrE | Metvu_0237 | Metvu_0163 | PFAM: phosphoribosyltransferase; KEGG: mja:MJ1646 orotate phosphoribosyltransferase-like protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.915 |
ACX72104.1 | pyrF | Metvu_0237 | Metvu_0701 | PFAM: phosphoribosyltransferase; KEGG: mja:MJ1646 orotate phosphoribosyltransferase-like protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.915 |
ACX72104.1 | pyrK | Metvu_0237 | Metvu_1175 | PFAM: phosphoribosyltransferase; KEGG: mja:MJ1646 orotate phosphoribosyltransferase-like protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Probable dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.917 |
ACX73198.1 | carA | Metvu_1345 | Metvu_1426 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: mja:MJ1381 carbamoyl-phosphate synthase, large subunit (carB2). | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: mfe:Mefer_0635 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
ACX73198.1 | pyrB | Metvu_1345 | Metvu_1447 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: mja:MJ1381 carbamoyl-phosphate synthase, large subunit (carB2). | KEGG: mfe:Mefer_0759 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region. | 0.998 |
ACX73198.1 | pyrC | Metvu_1345 | Metvu_1423 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: mja:MJ1381 carbamoyl-phosphate synthase, large subunit (carB2). | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.989 |
ACX73198.1 | pyrD | Metvu_1345 | Metvu_1011 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: mja:MJ1381 carbamoyl-phosphate synthase, large subunit (carB2). | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.882 |
ACX73198.1 | pyrE | Metvu_1345 | Metvu_0163 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: mja:MJ1381 carbamoyl-phosphate synthase, large subunit (carB2). | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.887 |
ACX73198.1 | pyrF | Metvu_1345 | Metvu_0701 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: mja:MJ1381 carbamoyl-phosphate synthase, large subunit (carB2). | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.872 |
ACX73198.1 | pyrG | Metvu_1345 | Metvu_0428 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: mja:MJ1381 carbamoyl-phosphate synthase, large subunit (carB2). | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.543 |
ACX73198.1 | pyrK | Metvu_1345 | Metvu_1175 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: mja:MJ1381 carbamoyl-phosphate synthase, large subunit (carB2). | Probable dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.880 |
carA | ACX73198.1 | Metvu_1426 | Metvu_1345 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: mfe:Mefer_0635 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: mja:MJ1381 carbamoyl-phosphate synthase, large subunit (carB2). | 0.999 |
carA | pyrB | Metvu_1426 | Metvu_1447 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: mfe:Mefer_0635 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | KEGG: mfe:Mefer_0759 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region. | 0.999 |
carA | pyrC | Metvu_1426 | Metvu_1423 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: mfe:Mefer_0635 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.998 |
carA | pyrD | Metvu_1426 | Metvu_1011 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: mfe:Mefer_0635 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.980 |
carA | pyrE | Metvu_1426 | Metvu_0163 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: mfe:Mefer_0635 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.977 |
carA | pyrF | Metvu_1426 | Metvu_0701 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: mfe:Mefer_0635 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.977 |
carA | pyrG | Metvu_1426 | Metvu_0428 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: mfe:Mefer_0635 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.420 |