STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72066.1PFAM: conserved hypothetical protein; KEGG: mfe:Mefer_0504 hypothetical protein. (313 aa)    
Predicted Functional Partners:
ACX72065.1
PFAM: protein of unknown function DUF112 transmembrane; KEGG: mja:MJ1079 hypothetical protein.
 
   
 0.949
ACX72031.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: mja:MJ1116 asparagine synthetase (AsnB).
     
 0.720
ACX72676.1
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: mja:MJ0417 hypothetical protein.
 
     0.661
ACX72953.1
PFAM: phosphoesterase PA-phosphatase related; SNARE associated Golgi protein; SMART: phosphoesterase PA-phosphatase related; KEGG: mja:MJ0374 lipoprotein B (LppB).
  
  
 0.661
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.657
ACX72064.1
KEGG: mfe:Mefer_0502 hypothetical protein.
       0.622
ACX73534.1
PFAM: Phosphomethylpyrimidine kinase; Phosphomethylpyrimidine kinase type-1; KEGG: mja:MJ0236 hypothetical protein.
  
    0.474
rad50
SMC domain protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
 
  
 0.451
ACX72098.1
PFAM: glycosyl transferase family 2; KEGG: mja:MJ1222 dolichol-P-glucose synthetase isolog.
 
  
 0.431
ACX72248.1
PFAM: glycosyl transferase group 1; KEGG: mfe:Mefer_0149 glycosyl transferase group 1.
 
  
 0.427
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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