STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACX72122.1PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: mfe:Mefer_0025 methyl-accepting chemotaxis sensory transducer. (610 aa)    
Predicted Functional Partners:
ACX72123.1
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: mfe:Mefer_0642 CheW protein.
 
 0.997
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.989
ACX72125.1
CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; CheW domain protein; SMART: Hpt domain protein; ATP-binding region ATPase domain protein; CheW domain protein; KEGG: mfe:Mefer_0640 CheA signal transduction histidine kinase.
 
 
 0.986
ACX72383.1
KEGG: mfe:Mefer_1107 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type.
 
 0.983
cheD
CheD, stimulates methylation of MCP protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
 0.976
ACX73350.1
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mfe:Mefer_1110 response regulator receiver protein.
 
 0.975
ACX73283.1
PFAM: chemotaxis sensory transducer; Rhodanese domain protein; SMART: chemotaxis sensory transducer; Rhodanese domain protein; KEGG: mmp:MMP0413 hypothetical protein.
 
  
0.917
ACX73348.1
PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: mfe:Mefer_1112 methyl-accepting chemotaxis sensory transducer.
  
  
 
0.903
ACX73351.1
PFAM: CheC domain protein; KEGG: mfe:Mefer_1109 CheC, inhibitor of MCP methylation.
 
 
 0.488
guaAA
GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.466
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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