Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACX72170.1PFAM: zinc/iron permease; KEGG: mja:MJ1036 hypothetical protein. (231 aa)    
Predicted Functional Partners:
ACX72953.1
PFAM: phosphoesterase PA-phosphatase related; SNARE associated Golgi protein; SMART: phosphoesterase PA-phosphatase related; KEGG: mja:MJ0374 lipoprotein B (LppB).
  
 
 0.732
ACX72284.1
PFAM: legume lectin beta domain; KEGG: mja:MJ1396 hypothetical protein.
  
     0.712
ACX73360.1
PFAM: Protein of unknown function DUF2341; KEGG: mja:MJ1470 hypothetical protein.
 
     0.707
ACX72275.1
PFAM: protein of unknown function DUF505; KEGG: mja:MJ1355 hypothetical protein.
  
     0.691
ACX72370.1
PFAM: Type II secretion system F domain; KEGG: mja:MJ1286 hypothetical protein.
 
   
 0.659
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
     0.654
ACX72769.1
Transcriptional regulator, TrmB; PFAM: domain of unknown function DUF1745; transcriptional regulator TrmB; KEGG: mja:MJ1623 hypothetical protein.
 
     0.645
ACX72211.1
PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: mja:MJ0687 hypothetical protein.
 
     0.622
ACX72281.1
PFAM: regulatory protein ArsR; transcriptional regulator TrmB; SMART: regulatory protein ArsR; KEGG: mja:MJ1398 hypothetical protein.
  
     0.615
ACX73320.1
PFAM: protein of unknown function DUF95 transmembrane; KEGG: mja:MJ0706 hypothetical protein.
 
    0.597
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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