Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72172.1PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0804 pyruvate formate-lyase activating enzyme (act). (287 aa)    
Predicted Functional Partners:
ACX72173.1
SMART: Hedgehog/intein hint domain protein; KEGG: mja:MJ0043 hypothetical protein.
       0.773
ACX73373.1
PFAM: protein of unknown function DUF366; KEGG: mfe:Mefer_1005 protein of unknown function DUF366.
       0.731
ACX72176.1
TIGRFAM: methanogenesis marker protein 17; PFAM: Uncharacterised conserved protein UCP019464, methanogenesis; KEGG: mja:MJ0802 hypothetical protein.
       0.709
ACX73027.1
KEGG: mja:MJ1599 hypothetical protein.
 
   
 0.703
pyrC
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.628
ACX73011.1
PFAM: peptidase U32; KEGG: mfe:Mefer_0733 peptidase U32.
 
  
 0.490
ACX72323.1
PFAM: Radical SAM domain protein; KEGG: dae:Dtox_0480 radical SAM domain protein.
 
     0.420
ACX73371.1
PFAM: extracellular solute-binding protein family 1; KEGG: mja:MJ1186 molybdate ABC transporter periplasmic substrate-binding protein.
 
  
 0.410
ACX73317.1
KEGG: mae:Maeo_0723 extracellular solute-binding protein.
 
  
 0.406
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.