STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72236.1PFAM: Protein of unknown function UPF0147; KEGG: mja:MJ1419 hypothetical protein; Belongs to the UPF0147 family. (93 aa)    
Predicted Functional Partners:
pfdB
Prefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
    0.675
albA
DNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.
  
     0.623
ACX71960.1
PFAM: Sjogrens syndrome scleroderma autoantigen 1; KEGG: mja:MJ0890 hypothetical protein.
       0.594
rps8e
TIGRFAM: ribosomal protein S8e; PFAM: Ribosomal protein S8E; KEGG: mja:MJ0673 30S ribosomal protein S8e.
  
    0.581
ACX73399.1
PFAM: Protein of unknown function DUF655; KEGG: mja:MJ0038 hypothetical protein.
  
     0.576
spt4
DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
  
    0.562
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
     0.559
ACX72234.1
KEGG: mja:MJ1049 hypothetical protein.
       0.522
ACX72962.1
PFAM: protein of unknown function DUF75; KEGG: mfe:Mefer_0348 protein of unknown function DUF75.
 
     0.474
ACX72648.1
PFAM: Radical SAM domain protein; KEGG: mja:MJ0619 hypothetical protein.
  
     0.456
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.