Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72266.1KEGG: mae:Maeo_0403 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. (457 aa)    
Predicted Functional Partners:
ACX73291.1
Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: mja:MJ0399 phosphomannomutase (PmmA); Belongs to the phosphohexose mutase family.
 
 0.978
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: mja:MJ1605 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.948
ACX71930.1
Nucleotide sugar dehydrogenase; KEGG: mja:MJ1054 UDP-glucose dehydrogenase, putative; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SMART: Hedgehog/intein hint domain protein.
 
 
 0.922
ACX72235.1
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; KEGG: mja:MJ1420 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) (GlmS); TIGRFAM: glucosamine/fructose-6-phosphate aminotransferase, isomerizing; PFAM: sugar isomerase (SIS); glutamine amidotransferase class-II; SMART: Hedgehog/intein hint domain protein.
    
 0.916
ACX73127.1
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: mja:MJ1101 glucose-1-phosphate thymidylyltransferase (StrD).
  
 
 0.911
ACX73263.1
TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: mja:MJ1334 UDP-glucose pyrophosphorylase (GtaB).
    
 0.901
fbp
Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
  0.900
ACX72738.1
UDP-N-acetylglucosamine 2-epimerase; KEGG: mja:MJ1504 lipopolysaccharide biosynthesis protein (WbpI); TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase.
    
 0.876
ACX73455.1
PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: mja:MJ0211 UDP-glucose 4-epimerase (GalE).
  
 
 0.849
ACX72031.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: mja:MJ1116 asparagine synthetase (AsnB).
     
 0.720
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.