STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
trm1N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (371 aa)    
Predicted Functional Partners:
truB
rRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
 
 0.910
ACX72271.1
KEGG: mja:MJ0945 hypothetical protein.
       0.905
ACX72218.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding domain protein; NOSIC domain protein; KEGG: mja:MJ0694 hypothetical protein.
 
  
 0.858
pus10
THUMP domain protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
 
   
 0.832
ACX72668.1
PFAM: THUMP domain protein; KEGG: mfe:Mefer_0032 THUMP domain protein.
  
 
 0.799
ACX72704.1
PFAM: THUMP domain protein; KEGG: mja:MJ0421 hypothetical protein.
   
 
 0.792
ACX73312.1
TIGRFAM: TIM-barrel protein; KEGG: mfe:Mefer_0497 TIM-barrel protein.
   
 
 0.763
ACX72817.1
TIGRFAM: RNA methylase, NOL1/NOP2/sun family; PFAM: Fmu (Sun) domain protein; KEGG: mfe:Mefer_1246 RNA methylase, NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.757
ACX73307.1
PFAM: putative RNA methylase; THUMP domain protein; DNA methylase N-4/N-6 domain protein; KEGG: mfe:Mefer_1079 putative RNA methylase.
  
 
 0.753
rpl24
Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
  
 
   0.752
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.