Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACX72278.1PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: mfe:Mefer_0598 DEAD/DEAH box helicase domain protein. (816 aa)    
Predicted Functional Partners:
ACX72277.1
PFAM: TrkA-N domain protein; Ion transport 2 domain protein; TrkA-C domain protein; KEGG: mja:MJ1357 potassium channel protein, putative.
  
    0.916
ACX72279.1
PFAM: Protein of unknown function DUF361; KEGG: mja:MJ1400 hypothetical protein.
       0.845
ACX72280.1
KEGG: mja:MJ1399 hypothetical protein; Belongs to the UPF0200 family.
 
     0.781
ACX72924.1
Transcriptional regulator, MarR family; PFAM: Helix-turn-helix type 11 domain protein; regulatory protein MarR; SMART: regulatory protein Crp; KEGG: mja:MJ0558 hypothetical protein.
 
     0.771
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
 
     0.757
ACX73387.1
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   
 0.709
ACX73393.1
PFAM: phosphoesterase RecJ domain protein; RNA binding S1 domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mja:MJ1198 hypothetical protein.
  
    0.701
rps8e
TIGRFAM: ribosomal protein S8e; PFAM: Ribosomal protein S8E; KEGG: mja:MJ0673 30S ribosomal protein S8e.
       0.678
ACX73094.1
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: mfe:Mefer_0782 pyruvate/ketoisovalerate oxidoreductase, gamma subunit.
       0.628
ACX72991.1
TIGRFAM: methanogenesis marker protein 14; PFAM: conserved hypothetical protein; KEGG: mja:MJ1451 hypothetical protein.
  
     0.604
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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