Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX72291.1PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; KEGG: mja:MJ0732 flavoprotein (FprA). (390 aa)    
Predicted Functional Partners:
ACX72292.1
KEGG: mja:MJ0733 hypothetical protein.
 
    0.934
ACX73173.1
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mja:MJ0649 NADH oxidase (nox).
    
 0.885
ACX72293.1
PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; KEGG: mja:MJ0734 rubrerythrin (rr).
 
  
 0.767
ACX72294.1
Rubredoxin-type Fe(Cys)4 protein; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
 
  
 0.685
ACX72299.1
Superoxide reductase; PFAM: Desulfoferrodoxin ferrous iron-binding region; KEGG: mja:MJ0741 desulfoferrodoxin, putative (rbo).
  
  
 0.660
ACX72296.1
KEGG: mja:MJ0737 rubredoxin-like non-heme iron protein.
 
  
 0.595
ACX72305.1
Hemerythrin-like metal-binding protein; Oxygen-binding protein. May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes. The oxygen- binding site contains two iron atoms; Belongs to the hemerythrin family.
  
  
 0.587
ACX72290.1
PFAM: NADPH-dependent FMN reductase; KEGG: mja:MJ0731 iron-sulfur flavoprotein (isf).
  
  
 0.582
ACX72295.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.509
ACX72304.1
PFAM: Rubrerythrin; KEGG: mja:MJ0746 hypothetical protein.
 
  
 0.484
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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