Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
speHS-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (124 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
 
 0.999
mat
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
     
 0.905
ACX72231.1
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: mja:MJ0563 modification methylase, type II R/M system; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
  0.900
ACX73189.1
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: mja:MJ1200 modification methylase, type II R/M system; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
  0.900
pdaD
KEGG: mja:MJ0316 pyruvoyl-dependent arginine decarboxylase; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family.
  
  
 0.879
secD
SecD/SecF/SecDF export membrane protein; Involved in protein export.
  
    0.668
ACX72268.1
PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: mja:MJ1105 trk system potassium uptake protein (TrkA).
     
 0.613
secF
SecD/SecF/SecDF export membrane protein; Involved in protein export.
  
    0.532
ACX72107.1
TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: mfe:Mefer_0143 agmatinase; Belongs to the arginase family.
     
 0.518
dys
Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
     
 0.460
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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