STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72363.1PFAM: PP-loop domain protein; KEGG: mfe:Mefer_1584 PP-loop domain protein. (342 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
       0.781
ACX73062.1
PFAM: PP-loop domain protein; KEGG: mfe:Mefer_0750 PP-loop domain protein.
  
  
 
0.656
ACX73116.1
PFAM: PP-loop domain protein; Queuosine synthesis-like; Thiamine biosynthesis protein-like; KEGG: mja:MJ1478 hypothetical protein.
  
  
 
0.647
ACX72365.1
PFAM: Protein of unknown function DUF553; KEGG: mja:MJ1282 hypothetical protein.
       0.531
ACX72037.1
PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: mja:MJ0134 L-isoaspartyl protein carboxyl methyltransferase isolog (PimT).
 
  
 0.530
ACX72823.1
KEGG: mja:MJ1136 hypothetical protein; TIGRFAM: histone acetyltransferase, ELP3 family; PFAM: Radical SAM domain protein; GCN5-related N-acetyltransferase; SMART: Elongator protein 3/MiaB/NifB.
   
 
 0.521
ACX72513.1
TIGRFAM: L-seryl-tRNA(Sec) kinase; PFAM: Chromatin associated protein KTI12; KEGG: mfe:Mefer_1539 L-seryl-tRNA(sec) kinase.
   
 
 0.464
ACX73032.1
PFAM: tRNA pseudouridine synthase D TruD; KEGG: mja:MJ1364 tRNA pseudouridine synthase D.
 
 
 0.450
rlmE
Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
  
  
 0.449
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.439
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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