Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX72386.1PFAM: protein of unknown function DUF116; KEGG: mja:MJ1141 hypothetical protein. (218 aa)    
Predicted Functional Partners:
ACX72385.1
KEGG: mja:MJ1142 arsenical pump-driving ATPase (ArsA); TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase.
     
 0.825
cbiX
Cobalamin (vitamin B12) biosynthesis CbiX protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
 
     0.634
ACX73582.1
Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
       0.585
ACX73102.1
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; ferredoxin; KEGG: mja:MJ0092 succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
       0.566
ACX73085.1
KEGG: mja:MJ0304 ferripyochelin binding protein (fbp).
       0.467
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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