STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72394.1TIGRFAM: methanogenesis marker protein 6; PFAM: conserved hypothetical protein; KEGG: mja:MJ0498 hypothetical protein. (155 aa)    
Predicted Functional Partners:
hjc
Resolvase, Holliday junction-type; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family.
  
    0.970
ACX72623.1
TIGRFAM: methanogenesis marker protein 3; KEGG: mja:MJ1412 hypothetical protein; Belongs to the UPF0288 family.
 
    0.901
ACX72689.1
TIGRFAM: methanogenesis marker protein 5; PFAM: conserved hypothetical protein; KEGG: mfe:Mefer_1315 methanogenesis marker protein 5.
 
     0.894
ACX73104.1
TIGRFAM: methanogenesis marker protein 7; PFAM: Protein of unknown function UCP019164; KEGG: mja:MJ0094 methyl coenzyme M reductase II, operon protein C (MtrC).
 
     0.894
ACX72981.1
KEGG: mja:MJ1242 methyl coenzyme M reductase system, component A2 (AtwA); TIGRFAM: methyl coenzyme M reductase system, component A2; PFAM: ABC transporter related; SMART: AAA ATPase.
 
     0.883
ACX72178.1
TIGRFAM: methanogenesis marker protein 15; CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: mfe:Mefer_1002 methanogenesis marker protein 15.
 
     0.856
ACX72015.1
TIGRFAM: methyl-coenzyme M reductase I operon protein C; PFAM: Methyl-coenzyme M reductase protein C; KEGG: mja:MJ0844 methyl coenzyme M reductase I, operon protein C (McrC).
 
     0.824
ACX72688.1
PFAM: conserved hypothetical protein; KEGG: mja:MJ0405 hypothetical protein.
 
     0.796
ACX72176.1
TIGRFAM: methanogenesis marker protein 17; PFAM: Uncharacterised conserved protein UCP019464, methanogenesis; KEGG: mja:MJ0802 hypothetical protein.
 
     0.794
ACX72017.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
     0.758
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.