STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72483.1PFAM: Radical SAM domain protein; KEGG: mja:MJ0808 pyruvate-formate-lyase-activating enzyme (act). (333 aa)    
Predicted Functional Partners:
ACX71954.1
PFAM: AMMECR1 domain protein; KEGG: mja:MJ0810 hypothetical protein.
     0.970
ACX72484.1
PFAM: protein of unknown function DUF98; KEGG: mja:MJ0807 hypothetical protein.
  
    0.928
ACX73287.1
PFAM: protein of unknown function DUF52; KEGG: mja:MJ0403 hypothetical protein; Belongs to the MEMO1 family.
     0.921
ACX71999.1
KEGG: mfe:Mefer_0922 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein.
  
  
 0.681
ACX72815.1
PFAM: conserved hypothetical protein; KEGG: mja:MJ1595 hypothetical protein.
 
     0.618
ACX71989.1
TIGRFAM: S-layer protein; PFAM: S-layer family protein; KEGG: mfe:Mefer_0912 S-layer protein.
       0.594
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.594
ACX73092.1
KEGG: mfe:Mefer_0784 hypothetical protein.
       0.594
ACX72173.1
SMART: Hedgehog/intein hint domain protein; KEGG: mja:MJ0043 hypothetical protein.
       0.573
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
  
 0.490
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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