STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX72487.1KEGG: mja:MJ0728 carbon monoxide dehydrogenase, catalytic subunit (CooS); TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane. (628 aa)    
Predicted Functional Partners:
cdhD
CO dehydrogenase/acetyl-CoA synthase, delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
 
  
 0.960
cdhA
CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
     
 0.949
cdhC
CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
 
  
 0.948
cdhE
CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
  
  
  0.945
ACX73019.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0265 carbon monoxide dehydrogenase, iron sulfur subunit CooF-1 (cooF2).
    
 0.924
ACX71990.1
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: mja:MJ0823 CODH nickel-insertion accessory protein CooC (CooC).
 
   
 0.919
ACX73020.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0264 carbon monoxide dehydrogenase, iron sulfur subunit CooF-1 (cooF1).
    
 0.914
ACX73043.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
    
 0.914
ACX73021.1
Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: mja:MJ1353m formate dehydrogenase.
    
 0.913
ACX72569.1
PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; KEGG: mja:MJ0006 formate dehydrogenase, alpha subunit.
    
 0.911
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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