STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72561.1PFAM: protein of unknown function DUF105; KEGG: mja:MJ1613 hypothetical protein. (261 aa)    
Predicted Functional Partners:
ACX72562.1
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: mja:MJ1614 hypothetical protein.
       0.936
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
   
 0.594
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
   
 0.588
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
     0.586
ACX72615.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mfe:Mefer_1140 ABC transporter related.
 
   
 0.585
ACX72789.1
KEGG: mfe:Mefer_0301 GTP:adenosylcobinamide-phosphate guanylyltransferase-like protein.
 
     0.560
ACX72564.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: mja:MJ1144 cobalamin biosynthesis protein (CbiG).
     
 0.520
ACX72103.1
PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: mja:MJ1598 hypothetical protein; Belongs to the UPF0284 family.
     
 0.503
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Allinase-like; aminotransferase class V; KEGG: mfe:Mefer_0844 histidinol-phosphate aminotransferase.
       0.481
ACX73119.1
PFAM: CobN/magnesium chelatase; KEGG: mfe:Mefer_0187 magnesium chelatase.
 
   
 0.455
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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