Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACX72571.1KEGG: mja:MJ1194m formylmethanofuran dehydrogenase (tungsten), subunit B, selenocysteine-containing; TIGRFAM: formylmethanofuran dehydrogenase subunit B; PFAM: molybdopterin oxidoreductase. (441 aa)    
Predicted Functional Partners:
ACX72657.1
TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3; KEGG: mja:MJ1169 formylmethanofuran dehydrogenase, subunit A (tungsten) (FwdA).
 
 0.996
ACX72658.1
PFAM: molydopterin dinucleotide-binding region; KEGG: mja:MJ1168 formylmethanofuran dehydrogenase, subunit D (tungsten) (FwdD).
 
 
 0.995
ACX72655.1
KEGG: mja:MJ1171 formylmethanofuran dehydrogenase, subunit C (tungsten) (FwdC); TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase alpha subunit domain protein.
 
 0.992
ftr
Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
 
 0.991
ACX72660.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ1166 formylmethanofuran dehydrogenase, subunit F (tungsten) (FwdF).
 
 0.987
ACX72659.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mfe:Mefer_0157 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
 
  0.984
ACX72569.1
PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; KEGG: mja:MJ0006 formate dehydrogenase, alpha subunit.
 
 0.970
ACX73338.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.963
ACX72568.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0005 formate dehydrogenase, beta subunit.
 
 0.958
ACX73341.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ1192m methylviologen-reducing hydrogenase, alpha subunit.
  
 
 0.958
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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