STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72574.1PFAM: nickel-dependent hydrogenase large subunit; KEGG: mae:Maeo_0097 nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (479 aa)    
Predicted Functional Partners:
ACX72575.1
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: mae:Maeo_0098 NADH ubiquinone oxidoreductase 20 kDa subunit.
 
 
 0.999
ACX72572.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.990
ACX72576.1
PFAM: methyl-viologen-reducing hydrogenase delta subunit; KEGG: mae:Maeo_0099 methyl-viologen-reducing hydrogenase delta subunit.
  
 
 0.974
ACX73340.1
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: mja:MJ1191 methylviologen-reducing hydrogenase, gamma chain (VhuG).
 
 
 0.974
ACX72489.1
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0726 coenzyme F420-reducing hydrogenase, gamma subunit.
  
 
 0.972
ACX72573.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ1193 polyferredoxin (MvhB).
  
 
 0.948
ACX73137.1
TIGRFAM: coenzyme F420 hydrogenase, subunit gamma; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0031 coenzyme F420-reducing hydrogenase, gamma subunit.
 
 
 0.942
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.884
ACX73338.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.858
ACX72148.1
TIGRFAM: CoB/CoM heterodisulfide reductase, subunit C; KEGG: mja:MJ0864 heterodisulfide reductase, subunit C2 (hdrC2).
  
 
 0.856
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.