STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ACX72580.1Phosphonopyruvate decarboxylase-related protein; KEGG: mja:MJ0010 BcpC phosphonopyruvate decarboxylase; TIGRFAM: phosphonopyruvate decarboxylase-related protein; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein. (426 aa)    
Predicted Functional Partners:
pgk
PFAM: phosphoglycerate kinase; KEGG: mja:MJ0641 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.923
ACX73280.1
KEGG: mja:MJ1018 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; 6-phosphogluconate dehydrogenase NAD-binding.
 
  
 0.923
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.922
apgM
Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
  
0.914
ACX73370.1
PFAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; KEGG: mja:MJ1185 putative aldehyde ferredoxin oxidoreductase (aor).
    
  0.903
fbp
Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
 
  
 0.860
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: mja:MJ1605 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.858
ACX72233.1
PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mfe:Mefer_0658 fructose-bisphosphate aldolase.
     
 0.822
aroA
Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
     
 0.822
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
     
 0.822
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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