STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
uppSUndecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (262 aa)    
Predicted Functional Partners:
ACX72144.1
PFAM: Polyprenyl synthetase; KEGG: mja:MJ0860 bifunctional short chain isoprenyl diphosphate synthase (IdsA); Belongs to the FPP/GGPP synthase family.
 
 
 0.989
ACX72589.1
KEGG: mja:MJ1373 hypothetical protein.
       0.928
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
  
    0.828
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.814
ACX72047.1
PFAM: putative RNA methylase; THUMP domain protein; KEGG: mja:MJ0438 hypothetical protein.
 
    0.803
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.776
ACX72587.1
TIGRFAM: methanogen marker protein 4; KEGG: mfe:Mefer_0014 methanogen marker protein 4.
  
    0.775
ACX72927.1
PFAM: peptidase M50; KEGG: mja:MJ0971 hypothetical protein.
  
  
 0.760
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.741
ACX72586.1
TIGRFAM: methanogenesis marker protein 12; KEGG: mja:MJ1370 hypothetical protein; Belongs to the UPF0285 family.
       0.731
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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