STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72594.1TIGRFAM: methanogenesis marker 13 metalloprotein; KEGG: mja:MJ1423 vanadium nitrogenase-associated protein N. (357 aa)    
Predicted Functional Partners:
ACX72693.1
PFAM: Mur ligase middle domain protein; KEGG: mfe:Mefer_0369 Mur ligase middle domain protein.
 
  
 0.988
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
  
 
 0.876
nifH-2
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
  
 
 0.876
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
    
 0.795
ACX72017.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
   
 0.774
ACX73052.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
   
 0.774
ACX72016.1
KEGG: mfe:Mefer_0937 methyl-coenzyme M reductase, gamma subunit; TIGRFAM: methyl-coenzyme M reductase, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit.
 
   
 0.769
ACX73051.1
KEGG: mja:MJ0082 methyl coenzyme M reductase II, subunit gamma (MtrG); TIGRFAM: methyl-coenzyme M reductase, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit.
 
   
 0.768
ACX72013.1
KEGG: mja:MJ0842 methyl coenzyme M reductase I, subunit beta (McrB); TIGRFAM: methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit.
 
   
 0.766
ACX73050.1
KEGG: mja:MJ0081 methyl coenzyme M reductase II, subunit beta (MrtB); TIGRFAM: methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit.
 
   
 0.764
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.