STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72596.1PFAM: Malate/L-lactate dehydrogenase; KEGG: mja:MJ1425 malate dehydrogenase. (345 aa)    
Predicted Functional Partners:
ACX73039.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: mfe:Mefer_0100 thiamine pyrophosphate protein domain protein TPP-binding.
    
 0.975
ACX72238.1
KEGG: mfe:Mefer_0815 2-phosphosulfolactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulfolactate phosphatase.
     
 0.962
ACX73374.1
KEGG: mja:MJ0255a sulfopyruvate decarboxylase subunit ComD.
    
 0.947
ACX72226.1
PFAM: Lactate/malate dehydrogenase; KEGG: mfe:Mefer_0722 malate dehydrogenase (NADP(+)); Belongs to the LDH/MDH superfamily.
    
 0.921
endA
tRNA intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
       0.853
ACX72597.1
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: mfe:Mefer_1395 putative signal transduction protein with CBS domains.
       0.483
purM
TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: mja:MJ0203 phosphoribosylaminoimidazole synthetase.
       0.478
ACX73000.1
PFAM: peptidase dimerisation domain protein; peptidase M20; KEGG: mja:MJ1497 acetylornithine deacetylase (ArgE).
 
  
 0.443
ACX72400.1
PFAM: Dimethylmenaquinone methyltransferase; KEGG: mja:MJ0644 S-adenosylmethionine:2-demethylmenaquinone methyltransferase (MenG).
 
   
 0.411
ACX73280.1
KEGG: mja:MJ1018 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; 6-phosphogluconate dehydrogenase NAD-binding.
     
 0.409
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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