STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72615.1PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mfe:Mefer_1140 ABC transporter related. (374 aa)    
Predicted Functional Partners:
ACX72616.1
PFAM: transport system permease protein; KEGG: mja:MJ0876 iron(III) dicitrate transport system permease protein.
 
 
 0.953
ACX72617.1
PFAM: transport system permease protein; KEGG: mja:MJ0877m iron III dicitrate ABC transporter, permease protein.
 
 
 0.952
ACX72835.1
PFAM: transport system permease protein; inner-membrane translocator; KEGG: mja:MJ0087 hemin permease (HemU).
 
 
 0.932
ACX72833.1
PFAM: periplasmic binding protein; KEGG: mja:MJ0085 iron transport periplasmic binding protein, putative (CeuE).
  
 
 0.925
ACX72614.1
PFAM: periplasmic binding protein; KEGG: mja:MJ0872 hypothetical protein.
 
     0.815
ACX72618.1
KEGG: mja:MJ0878 hypothetical protein.
 
     0.691
ACX72402.1
PFAM: periplasmic binding protein; KEGG: mja:MJ0642 hypothetical protein.
 
     0.683
ACX72561.1
PFAM: protein of unknown function DUF105; KEGG: mja:MJ1613 hypothetical protein.
 
   
 0.585
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
    
 0.497
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
     
 0.463
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (18%) [HD]