STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72627.1PFAM: Protein of unknown function DUF530; KEGG: mja:MJ1110 hypothetical protein. (486 aa)    
Predicted Functional Partners:
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
    0.878
ACX72626.1
PFAM: Protein of unknown function UPF0113; KEGG: mja:MJ1410 hypothetical protein.
       0.741
mptA
Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
       0.594
ACX72051.1
KH domain protein; KEGG: mja:MJ0443 putative RNA-processing protein; TIGRFAM: KH domain protein; PFAM: K Homology, type 1, subgroup; SMART: KH domain protein.
       0.594
ACX72052.1
KEGG: mfe:Mefer_0987 non-specific serine/threonine protein kinase; PFAM: RIO-like kinase; SMART: protein of unknown function RIO1.
       0.594
eif1a
Translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
       0.594
top6A
DNA topoisomerase (ATP-hydrolyzing); Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
       0.594
ACX72771.1
KEGG: mja:MJ1475 hypothetical protein.
       0.594
top6B
DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
       0.594
ACX73223.1
PFAM: Glycosyl transferase, family 4, conserved region; KEGG: mja:MJ1113 N-acetylglucosamine-1-phosphate transferase.
       0.586
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.