STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
ACX72629.1Translation initiation factor, aIF-2BII family; KEGG: mja:MJ0122 translation initiation factor IF-2B subunit delta; TIGRFAM: translation initiation factor, aIF-2BII family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related; Belongs to the eIF-2B alpha/beta/delta subunits family. (304 aa)    
Predicted Functional Partners:
eif2a
Translation initiation factor 2, alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
  
 0.972
rbcL
Ribulose bisphosphate carboxylase, type III; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
 
  
 0.971
ACX73127.1
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: mja:MJ1101 glucose-1-phosphate thymidylyltransferase (StrD).
   
 0.967
ACX72158.1
AMP phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
    
 0.933
ACX72391.1
TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; GTP-binding protein HSR1-related; KEGG: mja:MJ0495 EF-1 alpha family translation factor.
   
 0.884
ACX72601.1
PFAM: elongation factor Tu domain 2 protein; KEGG: mja:MJ0325 translation factor EF-1 alpha, putative.
   
 0.884
eif2g
Small GTP-binding protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
   
 0.884
ACX72687.1
PFAM: PfkB domain protein; KEGG: mja:MJ0406 ribokinase (RbsK); Belongs to the carbohydrate kinase PfkB family.
  
  
 0.781
hisS
KEGG: mfe:Mefer_1228 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 
 0.749
rpl40e
KEGG: mfe:Mefer_1082 hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 
 0.723
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.