STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72662.1Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: mja:MJ1164 hypothetical protein. (314 aa)    
Predicted Functional Partners:
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
 
     0.684
ACX73130.1
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: mja:MJ0586 hypothetical protein.
  
     0.608
mptD
Protein of unknown function DUF372; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
  
     0.596
ACX72530.1
PFAM: Protein of unknown function UPF0179; KEGG: mfe:Mefer_1322 protein of unknown function UPF0179; Belongs to the UPF0179 family.
  
     0.584
ACX72477.1
PFAM: PUA domain containing protein; SMART: PUA domain containing protein; KEGG: mja:MJ1022 queuine tRNA-ribosyltransferase.
  
     0.548
ACX72811.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0550 hypothetical protein.
  
     0.542
ACX71998.1
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mja:MJ0831 hypothetical protein.
  
     0.532
priS
DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
     0.530
carS
Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
     0.526
ACX72515.1
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mja:MJ0977 hypothetical protein.
  
     0.515
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.