Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72744.1PFAM: Protein of unknown function DUF54; KEGG: mfe:Mefer_0550 protein of unknown function DUF54; Belongs to the UPF0201 family. (131 aa)    
Predicted Functional Partners:
ACX72745.1
PFAM: protein of unknown function DUF87; HerA-ATP synthase, barrel domain; KEGG: mja:MJ1565 hypothetical protein.
       0.768
ACX73457.1
PFAM: Protein of unknown function DUF54; KEGG: mfe:Mefer_0467 protein of unknown function DUF54.
  
   
 0.723
ACX72280.1
KEGG: mja:MJ1399 hypothetical protein; Belongs to the UPF0200 family.
 
    0.704
ACX73451.1
PFAM: Protein of unknown function DUF137; KEGG: mja:MJ0209 hypothetical protein.
 
   
 0.624
ACX72958.1
PFAM: NMD3 family protein; KEGG: mja:MJ1650 hypothetical protein.
  
     0.619
ACX73219.1
PFAM: TOPRIM domain protein; SMART: Toprim sub domain protein; KEGG: mja:MJ1624 hypothetical protein; Belongs to the UPF0292 family.
 
     0.588
hisB
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: mfe:Mefer_1092 imidazoleglycerol-phosphate dehydratase.
       0.581
ACX73376.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0021 hypothetical protein.
  
     0.581
ACX72228.1
GHMP kinase; KEGG: mfe:Mefer_0856 GHMP kinase.
  
     0.558
ACX72060.1
PFAM: transcriptional regulator TrmB; KEGG: mja:MJ1082 hypothetical protein.
  
     0.544
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (40%) [HD]