STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
truBrRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (332 aa)    
Predicted Functional Partners:
ACX72218.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding domain protein; NOSIC domain protein; KEGG: mja:MJ0694 hypothetical protein.
 
 
 0.996
nop10
RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
   
 0.993
ACX71901.1
KEGG: mfe:Mefer_1022 hypothetical protein.
   
 0.990
rpl7ae
Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 0.988
infB
Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
 
 
 0.987
rps15
PFAM: Ribosomal S13S15 domain protein; ribosomal protein S15; KEGG: mfe:Mefer_1234 ribosomal S13S15 domain protein.
 
 
 0.969
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
 
 
 0.948
cmk
TIGRFAM: cytidylate kinase; KEGG: mja:MJ0656 cytidylate kinase.
      0.944
ACX72759.1
KEGG: mja:MJ0149 hypothetical protein.
       0.936
ACX73487.1
PFAM: RNA polymerase insert; RNA polymerase dimerisation; SMART: RNA polymerase RpoA/D/Rpb3-type; KEGG: mja:MJ0192 DNA-directed RNA polymerase, subunit D (RpoD).
 
 
 0.936
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.