Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72762.1PFAM: transcriptional regulator TrmB; KEGG: mja:MJ1503 hypothetical protein. (133 aa)    
Predicted Functional Partners:
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
  
    0.801
ACX72738.1
UDP-N-acetylglucosamine 2-epimerase; KEGG: mja:MJ1504 lipopolysaccharide biosynthesis protein (WbpI); TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase.
       0.724
ACX72477.1
PFAM: PUA domain containing protein; SMART: PUA domain containing protein; KEGG: mja:MJ1022 queuine tRNA-ribosyltransferase.
 
     0.622
ACX72770.1
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
       0.576
ACX72744.1
PFAM: Protein of unknown function DUF54; KEGG: mfe:Mefer_0550 protein of unknown function DUF54; Belongs to the UPF0201 family.
  
     0.496
ACX72620.1
KEGG: mja:MJ1488 hypothetical protein.
 
     0.495
ACX73457.1
PFAM: Protein of unknown function DUF54; KEGG: mfe:Mefer_0467 protein of unknown function DUF54.
  
     0.487
ACX73025.1
PFAM: amino acid-binding ACT domain protein; KEGG: mja:MJ1601 hypothetical protein.
  
     0.471
ACX73376.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mja:MJ0021 hypothetical protein.
  
     0.467
ACX72958.1
PFAM: NMD3 family protein; KEGG: mja:MJ1650 hypothetical protein.
  
    0.456
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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