STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72815.1PFAM: conserved hypothetical protein; KEGG: mja:MJ1595 hypothetical protein. (334 aa)    
Predicted Functional Partners:
ACX72610.1
KEGG: mja:MJ1596 3-isopropylmalate dehydrogenase 2 (leuB2); TIGRFAM: isopropylmalate/isohomocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase.
       0.875
ACX72814.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mja:MJ1367 sulfate transport ATP-binding protein (CysA).
  
    0.761
ACX72031.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: mja:MJ1116 asparagine synthetase (AsnB).
     
 0.720
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
     0.715
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
     0.696
ACX72227.1
PFAM: conserved hypothetical protein; KEGG: mja:MJ0491 hypothetical protein.
       0.670
ACX72953.1
PFAM: phosphoesterase PA-phosphatase related; SNARE associated Golgi protein; SMART: phosphoesterase PA-phosphatase related; KEGG: mja:MJ0374 lipoprotein B (LppB).
  
  
 0.661
ACX72483.1
PFAM: Radical SAM domain protein; KEGG: mja:MJ0808 pyruvate-formate-lyase-activating enzyme (act).
 
     0.618
ACX73092.1
KEGG: mfe:Mefer_0784 hypothetical protein.
       0.568
ACX73534.1
PFAM: Phosphomethylpyrimidine kinase; Phosphomethylpyrimidine kinase type-1; KEGG: mja:MJ0236 hypothetical protein.
  
    0.504
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.