STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX72873.1PFAM: nuclease (SNase domain protein); SMART: nuclease (SNase domain protein); KEGG: mja:MJ1439 thermonuclease. (192 aa)    
Predicted Functional Partners:
aroK
TIGRFAM: shikimate kinase; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: mja:MJ1440 shikimate kinase.
       0.877
ACX71999.1
KEGG: mfe:Mefer_0922 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein.
     
 0.747
rtcB
PFAM: protein of unknown function UPF0027; SMART: Hedgehog/intein hint domain protein; KEGG: mja:MJ0682 hypothetical protein; Belongs to the RtcB family.
     
 0.747
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
 
 0.686
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.673
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
   
 
 0.655
ACX72116.1
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: mfe:Mefer_1401 DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family.
   
 0.627
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
   
 0.627
ACX73481.1
KEGG: mja:MJ0198 hypothetical protein.
 
 
 
 0.611
rps10
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
   0.609
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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