STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACX73058.1KEGG: mfe:Mefer_1419 GTPase or GTP-binding protein-like protein. (363 aa)    
Predicted Functional Partners:
ACX72101.1
PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: mja:MJ0047 putative mRNA 3'-end processing factor 1.
   
 0.901
ACX73507.1
PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: mja:MJ0162 putative mRNA 3'-end processing factor 3.
   
 0.901
endA
tRNA intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
 
 0.890
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.881
ACX73060.1
PFAM: protein of unknown function DUF521; KEGG: mfe:Mefer_1421 protein of unknown function DUF521.
       0.881
ACX71891.1
PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat protein; KEGG: mba:Mbar_A3390 hypothetical protein.
  
 
 0.801
rpl40e
KEGG: mfe:Mefer_1082 hypothetical protein; Belongs to the eukaryotic ribosomal protein eL40 family.
     
  0.729
ACX73560.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mfe:Mefer_1094 radical SAM domain protein.
 
     0.678
tfb
Transcription factor TFIIB cyclin-releated protein; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
   
 
 0.636
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
   0.569
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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