Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ACX73062.1PFAM: PP-loop domain protein; KEGG: mfe:Mefer_0750 PP-loop domain protein. (305 aa)    
Predicted Functional Partners:
ACX73061.1
PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mja:MJ1159 replication factor A.
       0.823
ACX72037.1
PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: mja:MJ0134 L-isoaspartyl protein carboxyl methyltransferase isolog (PimT).
 
  
 0.701
ACX72823.1
KEGG: mja:MJ1136 hypothetical protein; TIGRFAM: histone acetyltransferase, ELP3 family; PFAM: Radical SAM domain protein; GCN5-related N-acetyltransferase; SMART: Elongator protein 3/MiaB/NifB.
   
 
 0.688
ACX72363.1
PFAM: PP-loop domain protein; KEGG: mfe:Mefer_1584 PP-loop domain protein.
  
  
 
0.656
ACX72927.1
PFAM: peptidase M50; KEGG: mja:MJ0971 hypothetical protein.
  
  
 0.620
ACX73116.1
PFAM: PP-loop domain protein; Queuosine synthesis-like; Thiamine biosynthesis protein-like; KEGG: mja:MJ1478 hypothetical protein.
  
  
 
0.618
ACX73236.1
PFAM: protein of unknown function Met10; KEGG: mja:MJ0883 hypothetical protein.
 
  
 0.606
ACX73063.1
KEGG: mja:MJ1158 hypothetical protein.
       0.551
rlmE
Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
 
  
 0.548
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
  
 0.499
Your Current Organism:
Methanocaldococcus vulcanius
NCBI taxonomy Id: 579137
Other names: M. vulcanius M7, Methanocaldococcus vulcanius M7, Methanocaldococcus vulcanius str. M7, Methanocaldococcus vulcanius strain M7
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